Therapeutic Approaches in Monkeypox Infections

Adelina-Gabriela Niculescu; Corneliu Ovidiu Vrancianu; Mara Madalina Mihai; Roxana-Elena Cristian; Iris Maria Tusa Iris Maria Tusa; Andreea Mihaela Sandu; Loredana Gabriela Popa Loredana Gabriela Popa; Mircea Ioan Popa; Marian Constantin; Monica Marilena Tantu

doi:10.25083/rbl/28.5/4135.4141

Autori

Adelina-Gabriela Niculescu Department of Science and Engineering of Oxide Materials and Nanomaterials, National University of Science and Technology Politehnica Bucharest , Autor
Corneliu Ovidiu Vrancianu Research Institute of the University of Bucharest—ICUB, University of Bucharest , Autor
Mara Madalina Mihai Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy , Autor
Roxana-Elena Cristian Research Institute of the University of Bucharest—ICUB, University of Bucharest , Autor
Iris Maria Tusa Iris Maria Tusa National Institute of Research and Development for Biological Sciences Autor
Andreea Mihaela Sandu Doctoral School, Carol Davila University of Medicine and Pharmacy , Autor
Loredana Gabriela Popa Loredana Gabriela Popa Universitatea de Medicină și Farmacie Carol Davila Autor
Mircea Ioan Popa Universitatea de Medicină și Farmacie Carol Davila Autor
Marian Constantin Institute of Biology of Romanian Academy , Autor
Monica Marilena Tantu Department of Medical Assistance and Physical Therapy, Pitesti University Center , Autor

DOI:

https://doi.org/10.25083/rbl/28.5/4135.4141

Cuvinte cheie:

monkeypox, therapeutic approaches, antiviral drugs, natural antivirals, nanotechnological solutions

Rezumat

Monkeypox virus, a zoonotic orthopoxvirus, has emerged as a significant global health concern following recent outbreaks in non-endemic regions. While previously confined to Central and West Africa, monkeypox virus has been recently detected worldwide, underscoring the need for enhanced surveillance and effective countermeasures. Moreover, no currently approved treatment for specific use in monkeypox infections exists. In this context, there is an urgent need to develop novel treatment options and strengthen global preparedness against monkeypox virus with innovative antiviral agents. Therefore, this paper provides an overview of the most recent therapeutic approaches aiming to deal with monkeypox virus infections. Notably, emerging synthetic-, natural-, and nanotechnological-based treatment strategies have been reviewed, creating an updated framework of use for future research studies.

Biografii autori

Adelina-Gabriela Niculescu, Department of Science and Engineering of Oxide Materials and Nanomaterials, National University of Science and Technology Politehnica Bucharest,

Research Institute of the University of Bucharest—ICUB, University of Bucharest
Corneliu Ovidiu Vrancianu, Research Institute of the University of Bucharest—ICUB, University of Bucharest,

National Institute of Research and Development for Biological Sciences

Doctoral School, Carol Davila University of Medicine and Pharmacy

Romanian Society of Bioengineering and Biotechnology
Mara Madalina Mihai, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy,

Department of Oncologic Dermathology, “Elias” University Emergency Hospital
Roxana-Elena Cristian, Research Institute of the University of Bucharest—ICUB, University of Bucharest,

National Institute of Research and Development for Biological Sciences

Romanian Society of Bioengineering and Biotechnology
Andreea Mihaela Sandu, Doctoral School, Carol Davila University of Medicine and Pharmacy,

The County Emergency Hospital, Pitești, Romania
Mircea Ioan Popa, Universitatea de Medicină și Farmacie Carol Davila

Cantacuzino National Military Medical Institute for Research and Development
Monica Marilena Tantu, Department of Medical Assistance and Physical Therapy, Pitesti University Center,

Faculty of Science, Physical Education and Informatics, National University of Science and Technology, Politehnica