Investigation of the antitumoral activity of Arthrospira platensis (Spirulina platensis) in mice

Abstract

In this study, the anti-tumoral effect of S. platensis was investigated in Balb-c mice with EAT (Ehrlich Acid Tumor). S. platensis was applied in the form of 200 mg/kg and 800 mg/kg concentrate. Blood taken from mice was separated into their serum and TAL (Total Antioxidant Level), TOL (Total Oxidant Level), ALT (Alanine Aminotransferase) and AST (Aspartate Aminotransferase) parameters were studied. Kidney, stomach, small intestine and large intestine tissues of the sacrificed subjects were removed and evaluated pathologically. As a result, when the biochemical values of S. platensis activity and control groups were compared statistically there was no statistically significant difference, excepting TOL. Also, in the pathological evaluation, the spread of the tumor in organs such as the large intestine and stomach was statistically significantly different.