Lifestyle features as co-factors in head and neck cancer development

Authors

  • MARIAN CONSTANTIN Institute of Biology of Romanian Academy, Bucharest, Romania Author
  • ROXANA ELENA CRISTIAN Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest Author
  • IOANA CRUNTEANU Faculty of Medicine, Titu Maiorescu University, Bucharest, Romania Author
  • SORIN TUDORACHE Faculty of Medicine, Titu Maiorescu University, Bucharest, Romania Author
  • CORNELIU OVIDIU VRANCIANU The Research Institute of the University of Bucharest, ICUB, Bucharest, Romania Author

DOI:

https://doi.org/10.25083/rbl/28.2/3950.3958

Keywords:

lifestyle factors, genetic aberration, pro-inflammatory food, chemical compounds

Abstract

Ranked sixth most prevalent worldwide, head and neck cancers (HNCs) affect an increasing number of people. Several factors contribute to their occurrence, including genetic and epigenetic aberrations and lifestyle factors, including heavy smoking, alcohol consumption, chewing betel quid (Areca nuts), poor oral hygiene, consumption of pro-inflammatory foods, inhalation of chemical compounds, asbestos dust, and infections with HPV (human papillomavirus) and EBV (Epstein-Barr virus). Often
diagnosed in advanced stages, they have a mortality rate of about 50% at 5 years and pose a serious threat to human health.

Author Biographies

  • MARIAN CONSTANTIN, Institute of Biology of Romanian Academy, Bucharest, Romania

    The Research Institute of the University of Bucharest, ICUB, Bucharest, Romania

  • CORNELIU OVIDIU VRANCIANU, The Research Institute of the University of Bucharest, ICUB, Bucharest, Romania

    Microbiology Immunology Department, Faculty of Biology, University of Bucharest
    National Institute of Research and Development for Biological Sciences, Bucharest

RBL282-7

Published

2024-07-01

Issue

Vol. 28 No. 2 (2023): Romanian Biotechnological Letters

Section

Articles