Therapeutic Approaches in Monkeypox Infections

Authors

  • Adelina-Gabriela Niculescu Department of Science and Engineering of Oxide Materials and Nanomaterials, National University of Science and Technology Politehnica Bucharest , Author
  • Corneliu Ovidiu Vrancianu Research Institute of the University of Bucharest—ICUB, University of Bucharest , Author
  • Mara Madalina Mihai Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy , Author
  • Roxana-Elena Cristian Research Institute of the University of Bucharest—ICUB, University of Bucharest , Author
  • Iris Maria Tusa National Institute of Research and Development for Biological Sciences image/svg+xml Author
  • Andreea Mihaela Sandu Doctoral School, Carol Davila University of Medicine and Pharmacy , Author
  • Loredana Gabriela Popa Carol Davila University of Medicine and Pharmacy image/svg+xml Author
  • Mircea Ioan Popa Carol Davila University of Medicine and Pharmacy image/svg+xml Author
  • Marian Constantin Institute of Biology of Romanian Academy , Author
  • Monica Marilena Tantu Department of Medical Assistance and Physical Therapy, Pitesti University Center , Author

DOI:

https://doi.org/10.25083/rbl/28.5/4135.4141

Keywords:

monkeypox, therapeutic approaches, antiviral drugs, natural antivirals, nanotechnological solutions

Abstract

Monkeypox virus, a zoonotic orthopoxvirus, has emerged as a significant global health concern following recent outbreaks in non-endemic regions. While previously confined to Central and West Africa, monkeypox virus has been recently detected worldwide, underscoring the need for enhanced surveillance and effective countermeasures. Moreover, no currently approved treatment for specific use in monkeypox infections exists. In this context, there is an urgent need to develop novel treatment options and strengthen global preparedness against monkeypox virus with innovative antiviral agents. Therefore, this paper provides an overview of the most recent therapeutic approaches aiming to deal with monkeypox virus infections. Notably, emerging synthetic-, natural-, and nanotechnological-based treatment strategies have been reviewed, creating an updated framework of use for future research studies.

Author Biographies

  • Adelina-Gabriela Niculescu, Department of Science and Engineering of Oxide Materials and Nanomaterials, National University of Science and Technology Politehnica Bucharest,

    Research Institute of the University of Bucharest—ICUB, University of Bucharest

  • Corneliu Ovidiu Vrancianu, Research Institute of the University of Bucharest—ICUB, University of Bucharest,

    National Institute of Research and Development for Biological Sciences

    Doctoral School, Carol Davila University of Medicine and Pharmacy

    Romanian Society of Bioengineering and Biotechnology

  • Mara Madalina Mihai, Faculty of Medicine, “Carol Davila” University of Medicine and Pharmacy,

    Department of Oncologic Dermathology, “Elias” University Emergency Hospital

  • Roxana-Elena Cristian, Research Institute of the University of Bucharest—ICUB, University of Bucharest,

    National Institute of Research and Development for Biological Sciences

    Romanian Society of Bioengineering and Biotechnology

  • Andreea Mihaela Sandu, Doctoral School, Carol Davila University of Medicine and Pharmacy,

    The County Emergency Hospital, Pitești, Romania

  • Mircea Ioan Popa, Carol Davila University of Medicine and Pharmacy

    Cantacuzino National Military Medical Institute for Research and Development

  • Monica Marilena Tantu, Department of Medical Assistance and Physical Therapy, Pitesti University Center,

    Faculty of Science, Physical Education and Informatics, National University of Science and Technology, Politehnica

RBL28_5-6

Published

2025-07-02

Issue

Vol. 28 No. 5 (2023): Romanian Biotechnological Letters

Section

Review

How to Cite

Therapeutic Approaches in Monkeypox Infections. (2025). Romanian Biotechnological Letters, 28(5). https://doi.org/10.25083/rbl/28.5/4135.4141

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